The A572, Leigh Road in Worsley has been closed and taped off in both directions by police after what is being described as a serious incident.
The road has been closed at the junction of Simpson Road and Booth Hall Way after what witnesses describe as a huge crash having happened at around 6:30pm this evening.
Diversions are in place around the area as police deal with the incident and drivers are being asked to avoid the area.
Up to 10 police vehicles are said to have arrived at the scene, including a special operations incident command van.
As yet it is unknown as to the nature of the incident but police are asking anyone heading into the area to find and alternative route.
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